World Cancer Day: The effectiveness of the HPV vaccine in preventing cancer is added to the scientific prevention of cervical cancer. Vaccine selection should focus on the cancer prevention effect.
February 4th is the 25th World Cancer Day. The theme is “Integrating health resources and sharing medical care for everyone”. It aims to increase people’s awareness of the importance of cancer prevention and treatment and encourage the whole society to actively prevent, detect and treat cancer. Just recently, data from a Scottish real-world study on the effectiveness of the human papillomavirus (HPV) vaccine in preventing cervical cancer was published in the Journal of the National Cancer Institute and attracted widespread attention. The study found that more than ten years after vaccination, no cases of cervical cancer were recorded among women aged 12-13 who received the imported bivalent HPV vaccine; three doses of the vaccine in those over 14 years old can also reduce the risk of cervical cancer.
Cervical cancer is mainly caused by persistent infection of high-risk HPV in the female reproductive tract. It has become the malignant tumor of the female reproductive tract with the highest incidence rate. There are approximately 600,000 new cases worldwide every year. In China alone, nearly 60,000 women will die from cervical cancer in 2020. However, cervical cancer is currently the only malignant tumor with a clear cause that is preventable and controllable.
This data comes from the HPV vaccine immunization program launched in Scotland in 2008. At the beginning of the project, imported bivalent HPV vaccines were introduced for routine vaccination of girls aged 12-13 years old, and catch-up vaccination for girls aged 14-18 years old. , the coverage rate of routine vaccination is as high as over 80%. Researchers collected nearly 450,000 HPV vaccination information, cervical cancer screening and diagnosis records of Scottish women and analyzed them. The results are exciting: more than ten years after vaccination, among the 12-13 year olds who are routinely vaccinated (all vaccinated Imported bivalent HPV vaccine), no cases of invasive cervical cancer have been recorded regardless of whether they are fully vaccinated. Based on this, it is estimated that the cancer prevention effect of the vaccine reaches 100%; in addition, for women who received three doses of the vaccine, regardless of their age, the cervical cancer The incidence of cancer is significantly lower than that of unvaccinated people.
“Cervical cancer is currently the only human cancer that can be eliminated. The results of this study further confirm the anti-cancer effectiveness of the imported bivalent HPV vaccine and are of great significance to the prevention and treatment practice of eliminating cervical cancer in my country.” Chinese Academy of Medical Sciences and Peking Union Medical College Professor Qiao Youlin from the School of Mass Medicine and Public Health said, “The anti-cancer effect is an important criterion for judging and selecting HPV vaccines. Women of appropriate age can choose the vaccine within reach as early as possible, strengthen cervical cancer screening at the same time, and establish scientific prevention measures for themselves in time. cancer protection.”
The main purpose of getting the HPV vaccine is to prevent cervical cancer. The main components of the HPV vaccine are antigens and adjuvants, which together determine the immune response after HPV vaccination, thereby affecting the overall anti-cancer effect of the vaccine; vaccines using innovative adjuvant systems (such as imported bivalent HPV vaccines) can help stimulate The body produces a stronger and broader immune response, thereby maintaining high and long-lasting antibody levels, which has a good anti-cancer effect.
